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MEGA, Molecular Evolutionary Genetics Analysis : ウィキペディア英語版
MEGA, Molecular Evolutionary Genetics Analysis

MEGA, Molecular Evolutionary Genetics Analysis, is a freely available software for conducting statistical analysis of molecular evolution and for constructing phylogenetic trees. The project for developing this software was initiated by the leadership of Masatoshi Nei in his laboratory at the Pennsylvania State University in collaboration with his graduate student Sudhir Kumar and postdoctoral fellow Koichiro Tamura.〔Kumar, S., K. Tamura, and M. Nei (1993) MEGA: Molecular Evolutionary Genetics Analysis. Ver. 1.0, The Pennsylvania State University, University Park, PA.〕 Nei wrote a monograph (pp. 130) outlining the scope of the software and presenting new statistical methods that were included in MEGA. The entire set of computer programs was written by Kumar and Tamura. Because the personal computers at that time did not have the capability of sending the monograph and the software electronically, they were delivered by postal mail. From the beginning, MEGA was intended to be an easy-to-use software and include solid statistical methods only.
MEGA version 2 (MEGA2), which was coauthored by an additional investigator Ingrid Jakobson, was released in 2001.〔Kumar, S., K. Tamura, I. B. Jakobsen, and M. Nei (2001) MEGA2 : Molecular Evolutionary Genetics Analysis. Ver. 2.0, Bioinformatics 17:1244-1245.〕 All the computer programs and the readme files of this version could be sent electronically because of the advancement of computer technology. Around this time, the leadership of the MEGA project was taken over by Kumar (now at Arizona State University) and Tamura (now at Tokyo Metropolitan University). The monograph “Molecular Evolutionary Genetics Analysis” was often used as a textbook for new ways of studying molecular evolution.
MEGA has been updated and expanded several times (release history), and currently all these versions are available from the MEGA home page (). The method is widely used and cited (5th version has been cited over 25,000 times in 4 years).〔Tamura, K., Stecher, G., Peterson, D., Filipski, A., Kumar, S. (2013) MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0. Mol. Biol. Evol. 30:2725-2729.〕
==Release History==


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